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Breakthrough Relief with Ketamine Infusion Therapy

Safe, physician-led treatments in Columbus that deliver real results for depression, anxiety, and chronic pain—often within days, not months.
Schedule a free consultMeet Dr. Caldwell

Improvement in Symptoms

Ketamine Infusion Therapy was shown to have:

%

Response Rate

Depressive Symptoms within:

Hours After Infusion

MiNDSET Patients with Long-Term Results

%

Response Rate

At MiNDSET we believe:

We are in the midst of a mental health crisis.

Ketamine opens doors in your mind that can reveal information your conscious state can’t access.

Traditional medications and treatments aren’t enough for everyone.

The best treatment is done by an experienced physician in a safe and caring space.

Ketamine works better when integrated with therapy.

You’ve suffered long enough.

What our patients are saying

22 ⭐️⭐️⭐️⭐️⭐️ Reviews

  • I cannot begin to express how grateful I am for the incredible care I received from Dr. Caldwell at Mindset. After years of struggling with chronic pain that disrupted every... read more

    Sarah F Avatar Sarah F
    April 30, 2025

    Compassionate & Life-Changing Care at Mindset Integrative Ketamine Care I cannot say enough good things about my experience at Mindset Integrative Ketamine Care. From the very first meeting, Dr. Caldwell made... read more

    Anne Barrett Avatar Anne Barrett
    March 30, 2025

    Referred to Dr. Caldwell for a different form of treatment. Dr. Caldwell was exceptionally kind, knowledgeable, and forthcoming on what to except during and after the sessions. Always willing to... read more

    Cami Garcia Avatar Cami Garcia
    March 2, 2025
  • Dr. Caldwell thank you for presenting at our Perianesthesia Nursing Conference. Your knowledge, wisdom and experience within this growing field is invaluable and your willingness to share and... read more

    Kevin Yowell Avatar Kevin Yowell
    February 11, 2025

    Doctor Caldwell kindly presented to Ohio insurance underwriters last evening. He did a wonderful job of educating us on this very relevant topic. As insurance professionals we are seeing... read more

    Jill Wickliff Avatar Jill Wickliff
    November 30, 2024

    Doctor Caldwell kindly presented to Ohio insurance underwriters last evening. He did a wonderful job of educating us on this very relevant topic. As insurance professionals we are seeing... read more

    Jill Wickliff Avatar Jill Wickliff
    November 21, 2024
  • My experiences have all been exceptionally positive and helpful. Dr. Caldwell, a practicing anesthesiologist, is kind, proficient, skilled, and very professional. He cares about the overall experience... read more

    Maria Calderone Avatar Maria Calderone
    November 19, 2024

    After struggling for years with antidepressants that left me feeling more numb than anything, I researched desperately for something (ANYTHING!) to help and ketamine therapy kept popping up. Tbh,... read more

    Kiki T Avatar Kiki T
    September 30, 2024

    I cannot recommend this place enough. I have been receiving infusions for chronic pain for over 3 years and just transferred my care here. Dr. Caldwell is extremely knowledgeable and... read more

    Shannon Smith Avatar Shannon Smith
    September 26, 2024
  • After struggling for years with antidepressants that left me feeling more numb than anything, I researched desperately for something (ANYTHING!) to help and ketamine therapy kept popping up. Tbh,... read more

    Kiki Dee Avatar Kiki Dee
    September 26, 2024

    If you are seeking help with mental and physical pain, you are in the right place. Understand you are in reach of help. Imagine all the hardship you bare on your... read more

    tim colatruglio Avatar tim colatruglio
    August 30, 2024

    If you are seeking help with mental and physical pain, you are in the right place. Understand you are in reach of help. Imagine all the hardship you bare... read more

    tim colatruglio Avatar tim colatruglio
    August 26, 2024
  • Dr Caldwell is a godsend. Even though he is providing a cutting-edge therapy, his manner is like that of an old-school family physician. When I was at his... read more

    David Bentz CPA Avatar David Bentz CPA
    August 26, 2024

    Dr Caldwell is a godsend. Even though he is providing a cutting-edge therapy, his manner is like that of an old-school family physician. When I was at his... read more

    David Bentz CPA Avatar David Bentz CPA
    July 30, 2024

    Dr. Caldwell was patient, attentive and caring. He took the time to answer all our questions. Highly recommend him and his practice.

    Jennie Woodruff Avatar Jennie Woodruff
    July 26, 2024
  • Dr. Caldwell and Dr. M genuinely care for each client and their families. We felt at home the moment we stepped into the center (which is beautiful). Both doctors were... read more

    R S Avatar R S
    May 30, 2024

    I completed 6 infusion treatments with Dr. Caldwell, along with integration therapy work with Dr. M. Everything was fantastic. I had a lot of fear entering the treatments around the... read more

    Alex P Avatar Alex P
    May 30, 2024

    Exponentially more effective and efficient than SSRI medication! I completed my infusions about a month ago and it's made a dramatic difference in my life. My anxiety/depression was so bad... read more

    ryan forche Avatar ryan forche
    May 30, 2024
  • It’s hard to leave a google review that sufficiently expresses how helpful this was for me. These infusions helped me so much. I have dealt with depression on and off... read more

    Jocelyn Reynolds Avatar Jocelyn Reynolds
    May 30, 2024

    The ketamine infusions are comfortable, professional, and tailored to your specific needs. Dr Caldwell is extremely attentive. The real benefits for me were the breakthroughs I was able to make in... read more

    Austin Hoover Avatar Austin Hoover
    May 30, 2024

    I am very thankful that Dr. Caldwell, an Anesthesiologist Dr. with years of experience decided to go into providing Ketamine Integrative Therapy Treatments. Before I moved to Ohio I had... read more

    Brooke Lundquist Avatar Brooke Lundquist
    May 30, 2024

ketamine clinic | columbus, ohio

In a caring comfortable space

The MiNDSET Integrative Ketamine Care clinic creates a comprehensive and holistic approach to mental health care, offering hope and relief to patients who have struggled for far too long. Conditions that can be treated through ketamine therapy include depression,  treatment resistant depression (TRD), adolescent and teen depression, postpartum depression, anxiety, post-traumatic stress disorder (PTSD), bipolar disorder and other mental health and chronic pain related disorders.

Dr. Caldwell takes you on a tour.

Dr. David Caldwell

Anesthesiologist,
Founder of MiNDSET

The Healing MiNDSET Podcast

The Healing Mindset explores the science, safety, and impact of ketamine-assisted therapy, psychedelic medicine, and integrative mental health care. The podcast features insights from David Caldwell, M.D., a board-certified anesthesiologist with over 26 years of clinical experience.

As the founder of Mindset Integrative Ketamine Care Clinic, Dr. Caldwell brings medical precision and compassionate care to conversations about depression treatment, anxiety relief, trauma healing, and mental wellness through psychedelic-assisted therapy.

What the VA’s New Psychedelic Trials Mean for Veteran Mental Health—and Why Medical Oversight Matters

As a physician who has spent more than three decades treating patients with complex mental health and pain conditions, I know how urgently we need better solutions—especially for veterans living with PTSD, treatment-resistant depression, and anxiety disorders. That’s...

Microdosing Myths: Why Science Doesn’t Support the Hype

At MiNDSET, we’ve always grounded our care in clinical evidence and medical oversight—not in trends. The recent Neuropharmacology study by Prochazkova and colleagues (2025) underscores why that distinction matters.The Science Speaks: No Real Benefits from Microdosing...

Health Canada Recognizes Ketamine as a National Priority — What This Means for Mental Health Care

A major shift is underway. Health Canada has officially recognized ketamine as a National Priority Drug, marking a turning point in how this powerful therapy is understood and supported across the country. At MiNDSET Integrative Ketamine Care, we see this as more than...

“Are Psychedelics Ready to Stand Alone?”

What a New JAMA Study Reveals — and Why Integration Still Matters** In recent months, conversation around psychedelic medicine has shifted from curiosity to clinical seriousness. The latest editorial in JAMA — “Are Psychedelic Agents Ready for Prime Time as...

Psychiatrist Shortages and the Expanding Role of Primary Care in Depression Treatment

By Dr. David Caldwell, Founder of MiNDSET Integrative Ketamine Care Mental health disorders such as depression and anxiety continue to rise across the United States, yet the number of psychiatrists available to provide specialized care has not kept pace. Today, more...

Integrative Ketamine Care: Advancing Mental Health and Pain Treatment

By Dr. David Caldwell, Founder of MiNDSET Integrative Ketamine Care For decades, patients suffering from treatment-resistant depression (TRD), PTSD, anxiety, and chronic pain have faced a frustrating reality: traditional treatment options often fail to provide relief,...

Can I support my clients receiving KIT if I do not have formal or extensive training in this modality?

Ketamine Infusion Therapy Collaborative Community Conversation: Our Mission at MiNDSET At MiNDSET, we are committed to advancing the field of interventional psychiatry through evidence-based practice, professional collaboration, and ethical innovation. Our mission...

The Science of Ketamine & Neuroplasticity: A New Frontier in Mental Health

What Is Neuroplasticity? Neuroplasticity is the brain’s ability to reorganize itself by forming new neural connections throughout life. It’s how we learn new skills, form memories, and recover from trauma. In conditions like depression, anxiety, and PTSD,...

Healing From the Inside Out: A New Era of Trauma Therapy with MiNDSET

"What if the path to healing didn’t require you to talk it all out first—but to feel it, safely, in silence?" That’s the kind of radical, yet deeply human, idea at the heart of MiNDSET Integrative Ketamine Care, featured on this week’s episode of The Keri Croft Show....

If IV Ketamine is more effective, why isn’t it covered by insurance too?

Imagine doing everything “right” to treat your depression—trying medication after medication—only to find yourself in the same mental fog. For millions living with treatment‑resistant depression (TRD), that’s reality. A recent randomized clinical trial published in...

Now You Can Finance Ketamine Infusion Therapy

The quickest and easiest way to pay for Ketamine Infusion Therapy not covered by your insurance.

the two doctors at MiNDSET

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